SkinMedica® Products

Appropriate for: All skin types

Purpose: Rejuvenate skin

Results:

• Reduced appearance of fine lines and wrinkles
• Enhanced skin texture and tone

When to Apply: Morning and evening after cleansing and toning

Where to Apply: Face (neck and chest if desired)

Appropriate for: All skin types

Purpose: All-in-one, rejuvenating serum

Results:

• Reduced appearance of wrinkles
• Enhanced skin texture and tone
• Initial results occurred in 30 days with optimal results occurring in 90 days*

Study Participant Questionnaires Revealed That:

• 92% rated their skin as looking healthier and more youthful*

When to Apply: Morning and evening after cleansing and toning

Where to Apply: Entire face (neck and chest if desired)

Appropriate for: Normal to dry skin

Purpose: Improve smoothness and hydration around the eyes

Results: Reduced appearance of fine lines and wrinkles

When to Apply: Morning and evening, after applying treatment products and prior to applying your moisturizer

Where to Apply: Skin underneath the eyes and around the outside corners of the eye area. Avoid upper eyelid.

Appropriate for: All skin types

Purpose: Enhance skin tone, texture, and resiliency

Results:

• Diminished appearance of fine lines and coarse wrinkles
• Enhanced skin tone and texture

When to Apply: In the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, increasing frequency slowly until daily use is tolerated.

Where to Apply: Face (neck and chest if desired)

Caution: Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use a sunscreen and limit sun exposure while using this product and for a week following.

Appropriate for: All skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product

Purpose: Enhance skin tone, texture, and resiliency

Results:

• Diminished appearance of fine lines and coarse wrinkles
• Enhanced skin tone and texture

When to Apply: In the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, increasing frequency slowly until daily use is tolerated.

Where to Apply: Face (neck and chest if desired)

Caution: Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use a sunscreen and limit sun exposure while using this product and for a week following.

Appropriate for: All skin types

Purpose: Hydrates, refreshes and soothes

When to Apply: Replenish Hydrating Cream should be applied twice daily in the morning and evening. Apply after cleansing, toning and treatment products, and before sunscreen in the a.m.

Where to Apply: Evenly over entire face (neck and chest if desired). May also be used to soften, smooth and hydrate hands

How to Apply: Apply a small amount to back of hand, then use fingertip to apply

Appropriate for: Normal to oily skin

Provides: Facial hydration and improves the overall appearance of skin condition

When to Apply: Twice daily after cleansing, toning and applying treatment products

Where to Apply: Face (neck and chest if desired)

How to Apply: Apply a small amount into your hand and gently massage into skin

Appropriate for: Dry or post-procedure skin

Provides: Hydration, helps restore skin’s moisture balance

When to Apply: Twice daily after cleansing, toning and applying treatment products

Where to Apply: Face (neck and chest if desired)

How to Apply: Apply a small amount into your hand and gently massage into skin

Appropriate for: Normal to dry skin

Provides: Intense skin hydration and helps replenish moisture

When to Apply: Twice daily after cleansing, toning and applying treatment products

Where to Apply: Face (neck and chest if desired)

How to Apply: Apply a small amount into your hand and gently massage into skin

Appropriate for: All skin types

Purpose:Rejuvenating superscreen to prevent the appearance of premature aging from chronic exposure to infrared rays. Provides comprehensive protection beyond UVA and UVB while supporting the skin’s ability to restore itself.

Results:Powered by SOL-IR™ Advanced Antioxidant Complex to:
•Protect skin from harmful infrared rays (IR-A rays)
•Reduce the appearance of lines and wrinkles*
•Improve the appearance of damaged skin*

STUDY PARTICIPANT QUESTIONNAIRES REVEALED THAT:
•100% of users said TOTAL DEFENSE + REPAIR SPF 34 absorbs easily and quickly, does not leave white residue, spreads evenly (without lumps), and does not feel greasy (at week 4)*
•91% of users said TOTAL DEFENSE + REPAIR SPF 34 improves skin’s overall health and overall appearance (at week 8)*
•90% of users said that with TOTAL DEFENSE + REPAIR SPF 34 they saw improvement in skin firmness, tightness, and elasticity (at week 8)*

When to Apply: In the morning, as the last product in your regimen

Where to Apply:Entire face (neck and chest if desired), and other sun-exposed areas

How to Apply:Apply liberally 15 minutes before sun exposure. Reapply as needed or after towel drying, swimming, or perspiring. Children under 6 months of age, ask a doctor.

Active Ingredients:
•Octinoxate 7.5%
•Octisalate 3.0%
•Zinc Oxide 8.0%

Inactive Ingredients:
Water, Caprylic/Capric Triglyceride, Silica, Squalane, Glycerin, Niacinamide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Butyrospermum parkii (Shea) Butter, Polygonum aviculare Extract, Physalis angulata Extract, Dunaliella salina Extract, Ubiquinone, Camellia sinensis Leaf Extract, Tremella fuciformis Sporocarp Extract, Betaine, Melanin, Tocopheryl Acetate, Tocopherol, Hydroxyacetophenone, Batyl Alcohol, C12-15 Alkyl Benzoate, Panthenol, Butylene Glycol, Ceteareth-20, Polyhydroxystearic Acid, Isostearic Acid, Xanthan Gum, Ethylhexylglycerin, Disodium EDTA, Aminomethyl Propanol, Caprylyl Glycol, Potassium Sorbate, Sorbic Acid, Phenoxyethanol

Warning: For external use only. UV exposure from the sun increases the risk of skin cancer, premature skin aging and other skin damage. It is important to decrease UV exposure by limiting time in the sun, wearing protective clothing and using a sunscreen. When using this product, keep out of eyes. Rinse with water to remove. Do not use if allergic to any ingredient. Stop use and ask a doctor if rash or irritation develops and lasts. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Appropriate for: All skin types

Purpose:Rejuvenating superscreen to prevent the appearance of premature aging from chronic exposure to infrared rays. Provides comprehensive protection beyond UVA and UVB while supporting the skin’s ability to restore itself. Water resistant (80 minutes)

When to Apply: In the morning, as the last product in your regimen

Where to Apply:Entire face (neck and chest if desired), and other sun-exposed areas

How to Apply: Apply liberally 15 minutes before sun exposure. Reapply after 80 minutes of swimming or sweating, and immediately after towel drying at least every two hours.

Results: Powered by SOL-IR™ Advanced Antioxidant Complex to:
•Protect skin from harmful infrared rays (IR-A rays)
•Reduce the appearance of lines and wrinkles*
•Improve the appearance of damaged skin*

STUDY PARTICIPANT QUESTIONNAIRES REVEALED THAT:
•100% of users said TOTAL DEFENSE + REPAIR SPF 50+ absorbs easily and quickly, does not leave white residue, spreads evenly (without lumps), and does not feel greasy (at week 4)*
•91% of users said TOTAL DEFENSE + REPAIR SPF 50+ improves skin’s overall health and overall appearance (at week 8)*
•90% of users said that with TOTAL DEFENSE + REPAIR SPF 50+ they saw improvement in skin firmness, tightness, and elasticity (at week 8)*

Active Ingredients:
•Octinoxate 7.5%
•Octisalate 3.0%
•Zinc Oxide 8.0%

Inactive Ingredients:
Water, Caprylic/Capric Triglyceride, Silica, Squalane, Glycerin, Niacinamide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Butyrospermum parkii (Shea) Butter, Polygonum aviculare Extract, Physalis angulata Extract, Dunaliella salina Extract, Ubiquinone, Camellia sinensis Leaf Extract, Tremella fuciformis Sporocarp Extract, Betaine, Melanin, Tocopheryl Acetate, Tocopherol, Hydroxyacetophenone, Batyl Alcohol, C12-15 Alkyl Benzoate, Panthenol, Butylene Glycol, Ceteareth-20, Polyhydroxystearic Acid, Isostearic Acid, Xanthan Gum, Ethylhexylglycerin, Disodium EDTA, Aminomethyl Propanol, Caprylyl Glycol, Potassium Sorbate, Sorbic Acid, Phenoxyethanol

Warning: For external use only. UV exposure from the sun increases the risk of skin cancer, premature skin aging and other skin damage. It is important to decrease UV exposure by limiting time in the sun, wearing protective clothing and using a sunscreen. When using this product, keep out of eyes. Rinse with water to remove. Do not use if allergic to any ingredient. Stop use and ask a doctor if rash or irritation develops and lasts. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Appropriate for: All skin types

Purpose: Lytera® 2.0 is an advanced Pigment Correcting Serum, formulated to address the appearance of stubborn skin discoloration.

Key Benefits of Lytera® 2.0
Formulated to address even the most stubborn discoloration, regardless of skin type or genetic makeup. Improvements seen in as early as 2 weeks with progressively dramatic results at 12 weeks and beyond. Helps optimize results of multiple treatment approaches, including chemical peels, laser therapy, microdermabrasion, and prescription skin care products, such as hydroquinone

Non-hydroquinone, retinol-free, paraben-free, fragrance-free, non-comedogenic formulation

When to Apply: Apply one pump twice daily after cleansing and toning the skin, in the morning and evening, prior to applying moisturizer and sunscreen.

Where to Apply: Lytera^® 2.0 can be applied to the entire face, neck, chest, or other affected areas.

Caution: Keep out of direct sunlight.

What skin type is appropriate for Lytera^® 2.0 Pigment Correcting Serum?
Lytera^® 2.0  has been shown to reduce the appearance of even the most stubborn hyperpigmentation across diverse skin tones, types, and concerns.

Can Lytera^® 2.0 be used with no visible skin discoloration, but to only brighten one’s complexion?
Lytera^® 2.0 is designed to improve clarity, evenness, and overall appearance of most skin tones and types.

Does Lytera^® 2.0 work on acne-prone skin?
Lytera^® 2.0 is non-comedogenic and developed to work well on all skin types. The retinol-free, hydroquinone-free formulation is ideal for skin prone to irritation or inflammatory lesions.

What results are expected from using Lytera^® 2.0?
Clinical studies demonstrated the following results:

• Improved appearance of evenness of skin tone
• Improved overall appearance of the skin
• Increased radiance and clarity of the skin
• Lessened appearance of darker patches and discolorations

It’s important to note that results vary depending on severity and cause of hyperpigmentation. For optimal results, patients must comply with their recommended treatment plan, apply sunscreen daily as needed, and avoid excessive sun exposure.

How long until visible improvements can be expected?
In some cases, results were seen in as early as 2 weeks with increasingly dramatic improvements at week 4, 8, 12 and beyond. Results may vary depending on severity of condition. For optimal results, patients must adhere to treatment plan, use sunscreen daily, and avoid excessive sun exposure.

Is Lytera^® 2.0 safe for use with pregnant or breast-feeding patients?
The safety of our products has not been established in vulnerable populations, including women who are pregnant, planning to become pregnant, or breastfeeding. Standard cosmetic safety testing is conducted with our products in healthy adult human volunteers that are not pregnant. Lytera^® 2.0 does not contain any known teratogenic ingredients, ingredients known to harm mother and/or baby. Therefore, pregnancy is not considered a contraindication for Lytera^® 2.0.

Can I integrate Lytera® 2.0 into a 4% prescription strength hydroquinone regimen? Can Lytera® 2.0 also be used with chemical peels, laser treatments, or other cosmetic topical products?
Yes. Lytera® 2.0 was designed to work well as a monotherapy or to optimize other treatment approaches.

How long should patients wait before applying sunscreen?
Allow Lytera® 2.0 to absorb fully into the skin before applying sunscreen, approximately 3-5 minutes.

How long should patients use Lytera® 2.0?
In clinical studies, optimal results were achieved within 3 months and, in some cases, visible improvements were seen in as early as 2 weeks. However, since hyperpigmentation is a chronic condition that has no known cure, it must be constantly managed with an optimal treatment approach including daily application of SPF and avoidance of excess sun exposure. Use of Lytera® 2.0 is recommended as long as results are desired.

Should I use Lytera® 2.0 only as a spot treatment?
In clinical studies, the formula was shown to be effective when applied to the entire face and was not evaluated as a spot treatment.

How long should one (1) 2 oz Lytera® 2.0 bottle last?
A 2 oz bottle should last 8-10 weeks, if used according to package directions, 1 pump, twice daily (morning and evening).

What are proper storage conditions for Lytera® 2.0?
As with most SkinMedica® products, Lytera® 2.0 should be stored at room temperature 15-30 degrees Celsius (59-86 degrees Fahrenheit). Avoid exposure to extreme heat or cold.

HA⁵ Rejuvenating Hydrator Provides immediate smoothing in the appearance of fine lines and wrinkles, and supports the skin’s natural ability to replenish its own hyaluronic acid for overall skin health.

Key Benefits of HA⁵

• HA⁵ delivers both immediate and long-term benefits
• Instantly smoothes the appearance of fine lines and wrinkles
• Immediate hydration
• Improves the appearance of skin texture and roughness

Exponentially Smooth
Introducing a new chapter in skin hydration. HA⁵supports the skin’s ability to replenish its own HA for overall skin health. HA⁵ has a proprietary mix of five HA forms that smooth the skin, thereby decreasing the appearance of fine lines and wrinkles. The 5 HA’s work synergistically to provide immediate smoothing and continuous hydration throughout the day.

When to Apply
Apply twice daily—in the morning and at night—after cleansing, toning, and treating your skin. Apply before you moisturize and apply SPF (sun protection).

Where to Apply
Apply to face, neck and décolleté, or any area where fine lines and wrinkles primarily exist.

How to Apply
Because HA⁵ is a “water-loving” substance, wet your fingertips prior to applying HA⁵ to your skin.

Appropriate for: All skin types

Additional Information

What’s the difference between a moisturizer and a hydrator?
A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of both that prevent skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural ability to replenish HA.

Is HA⁵ Rejuvenating Hydrator oil free, fragrance free and non-comedogenic?
Yes, HA⁵ is oil free and fragrance free, and is appropriate for all skin types. HA⁵ is considered non-comedogenic.

Is it safe to use for a person with a milk allergy?
No. HA⁵ contains whey protein that is derived from milk powder. Therefore a person with a history of milk or whey protein allergy that triggers an immune response should not use this product because they may experience an allergic reaction.

How should HA⁵ Rejuvenating Hydrator be used within a regimen?
HA⁵ Rejuvenating Hydrator can be used with any SkinMedica^® product or regimen to support hydration. It should be applied immediately before moisturizer in a normal regimen.

Appropriate for: All skin types

Purpose: Sloughs off the top layer of skin to reveal fresh, new skin

When to Apply: Use 2 – 3 times a week, in the morning and in the evening as tolerated

Where to Apply: Evenly onto face (neck and chest if desired)

How to Apply: Moisten skin with lukewarm water. Apply a small amount to fingertips, add a little water and gently massage into face (neck and chest if desired). Rinse thoroughly with warm water. After cleansing and gently patting skin dry, apply other treatment products if you are using them, followed by moisturizer and sunscreen (a.m. only)

Sunburn Alert: These products contain an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using these products and for a week following.

Appropriate for: All skin types

Purpose: Encourages skin renewal and softness

When to Apply: In the evening after cleansing and applying other treatment products

Where to Apply: Evenly over entire face (neck and chest if desired)

How to Apply: Apply a small amount to back of hand then using fingertip and apply evenly over entire face

Sunburn Alert: These products contain an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using these products and for a week following.